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New tools make rogue genes easier to map

发布时间:2019-03-01 10:07:06来源:未知点击:

NOW that the human genome has been mapped, the next challenge is to discover when and where genes are switched on, and what happens when things go wrong. Thanks to a new two-pronged technique, that task may just have got easier. Joseph Ecker and colleagues at the Salk Institute in La Jolla, California, have streamlined the process of cataloguing where methylation – which switches genes off – occurs in the genome. They began by modifying an existing gene-sequencing method so that methylation sites could be detected more quickly. This generates huge amounts of data,