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Engineered tumour

发布时间:2019-03-07 11:04:09来源:未知点击:

FOR the first time, researchers have transformed a healthy human cell into a cancer cell by tweaking a few key genes. Scientists studying tumour cells have no way of knowing all the different mutations that make them divide uncontrollably. But Robert Weinberg and his colleagues at the Massachusetts Institute of Technology have turned a human cell cancerous by making it express three genes that they know are switched on in tumours (Nature, vol 400, p 464). “No one has ever been able to make a human cancer cell with a defined set of genes before,” says Weinberg. He hopes this will help researchers figure out how mutations interact to govern a tumour’s growth,